CV

Education

• M.D. in Medicine, National Taiwan University, 2011
• B.S. in Physics, National Taiwan University, 2011
• M.S. in Physics, National Taiwan University, 2014
• Ph.D in Biomedical Imaging, New York University, 2019

Work experience

• 2008-2009: Intern Physician
  • National Taiwan Univeristy Hospital, Taiwan
• 2011-2012: Medical Officer, Second Lieutenant
  • Matsu Beigan Field Hospital, Taiwan
• 2019-2021: Postdoctoral Fellow
  • New York University, School of Medicine, New York
  • Supervisor: Dr. Dmitry S Novikov and Dr. Els Fieremans
• 2021-2021: Research Fellow
  • Radiology, Mass General Hospital/Harvard Medical School, Boston
  • Supervisor: Dr. Susie Y Huang
• 2021-present: Instructor
  • Radiology, Mass General Hospital/Harvard Medical School, Boston

Honors and Awards

• 2021 NIH Director’s Early Independence Award
• 2021 ISMRM Junior Fellow
• 2020 Brain Structure and Function Editors Choice Award, Cajal Club
• 2019 Special MacCracken Award, New York University School of Medicine
• 2019 Trainee Competition, 2nd Place, White Matter Study Group, ISMRM 27th Annual Meeting
• 2018 Trainee Competition, 2nd Place, White Matter Study Group, ISMRM 26th Annual Meeting
• 2017 Trainee Competition, 3rd Place, White Matter Study Group, ISMRM 25th Annual Meeting
• 2016 Abstract Presenter Award, 2nd Place, Diffusion Study Group, ISMRM 24th Annual Meeting
• 2002 Gold Medal, 33rd International Physics Olympiad, Bali, Indonesia

Skills

• Time-dependent diffusion MRI
  • Biophysical modeling
  • Numerical validation
  • MRI experiment
• Image processing
  • Gibbs-ringing correction
  • Non-Cartesian sampling denoising
  • Super-resolution
• Computer: MATLAB, C++, CUDA C++

Publications

Along-axon diameter variation and axonal orientation dispersion revealed with 3D electron microscopy: implications for quantifying brain white matter microstructure with histology and diffusion MRI

Lee, H. H., Yaros, K., Veraart, J., et al. (2019). "Along-axon diameter variation and axonal orientation dispersion revealed with 3D electron microscopy: implications for quantifying brain white matter microstructure with histology and diffusion MRI." Brain Structure and Function, 224:1469–1488.

Effects of COVID-19 Prevention Measures on Other Common Infections, Taiwan

Lee, H. H., & Lin, S. H. (2020). "Effects of COVID-19 prevention measures on other common infections, Taiwan." Emerging infectious diseases, 26(10), 2509.

In vivo observation and biophysical interpretation of time-dependent diffusion in human cortical gray matter

Lee, H. H., Papaioannou, A., Novikov, D. S., & Fieremans, E. (2020). "In vivo observation and biophysical interpretation of time-dependent diffusion in human cortical gray matter." NeuroImage, 222, 117054.

The impact of realistic axonal shape on axon diameter estimation using diffusion MRI

Lee, H. H., Jespersen, S. N., Fieremans, E., & Novikov, D. S. (2020). "The impact of realistic axonal shape on axon diameter estimation using diffusion MRI." NeuroImage, 223, 117228.

Realistic Microstructure Simulator (RMS): Monte Carlo simulations of diffusion in three-dimensional cell segmentations of microscopy images

Lee, H. H., Fieremans, E., & Novikov, D. S. (2021). "Realistic Microstructure Simulator (RMS): Monte Carlo simulations of diffusion in three-dimensional cell segmentations of microscopy images." Journal of Neuroscience Methods, 350, 109018.

Removal of partial Fourier‐induced Gibbs (RPG) ringing artifacts in MRI

Lee, H. H., Novikov, D. S. & Fieremans, E. (2021). "Removal of partial Fourier-induced Gibbs (RPG) ringing artifacts in MRI." Magnetic Resonance in Medicine, 86:2733-2750.

The effects of axonal beading and undulation on axonal diameter estimation from diffusion MRI: Insights from simulations in human axons segmented from three-dimensional electron microscopy

Lee, H. H., Tian, Q., Sheft, M., et al. (2024). "The effects of axonal beading and undulation on axonal diameter estimation from diffusion MRI: Insights from simulations in human axons segmented from three-dimensional electron microscopy." NMR in Biomedicine, e5087.

Talks

How to Set Up Monte Carlo Simulations of Diffusion

August 11, 2020

Talk at 2020 ISMRM & SMRT Virtual Conference and Exhibition, virtual meeting

Tutorial: Microstructure Imaging

May 16, 2021

Talk at 2021 ISMRM & SMRT Virtual Conference and Exhibition, virtual meeting

Diffusion MRI Made Ridiculously Simple

October 07, 2021

Talk at 2021 Why & How, MGH Martinos Center for Biomedical Imaging, MGH Martinos Center for Biomedical Imaging

Beyond Standard Model/Time-Dependent Diffusion in Brain

October 12, 2022

Talk at 2022 ISMRM Workshop on Diffusion MRI: From Research to Clinic, Amsterdam, The Netherlands

Diffusion Numerical Phantoms

June 03, 2023

Talk at 2022 ISMRM & SMRT Virtual Conference and Exhibition, Toronto, ON, Canada